Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Catalysis02:50

Catalysis

28.9K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
28.9K
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

9.6K
For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...
9.6K
Radical Autoxidation01:20

Radical Autoxidation

2.6K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.6K
Woodward–Hoffmann Selection Rules and Microscopic Reversibility01:34

Woodward–Hoffmann Selection Rules and Microscopic Reversibility

3.5K
Electrocyclic reactions, cycloadditions, and sigmatropic rearrangements are concerted pericyclic reactions that proceed via a cyclic transition state. These reactions are stereospecific and regioselective. The stereochemistry of the products depends on the symmetry characteristics of the interacting orbitals and the reaction conditions. Accordingly, pericyclic reactions are classified as either symmetry-allowed or symmetry-forbidden. Woodward and Hoffmann presented the selection criteria for...
3.5K
Catalytically Perfect Enzymes01:07

Catalytically Perfect Enzymes

4.6K
The theory of catalytically perfect enzymes was first proposed by W.J. Albery and J. R. Knowles in 1976. These enzymes catalyze biochemical reactions at high-speed. Their catalytic efficiency values range from 108-109 M-1s-1. These enzymes are also called 'diffusion-controlled' as the only rate-limiting step in the catalysis is that of the substrate diffusion into the active site. Examples include triose phosphate isomerase, fumarase, and superoxide dismutase.
 
Most enzymes...
4.6K
Autophagy01:27

Autophagy

5.2K
Autophagy is a self-digesting process by which a cell protects itself from threats both within and outside the cell, ranging from abnormal proteins to invading bacteria. In this process, obsolete components of the cell and invading microbes are degraded by hydrolytic enzymes active in an acidic environment of the lysosomal lumen.
An autophagic pathway consists of a series of signaling events activated in response to diverse stress and physiological conditions such as food deprivation,...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autoinhibition in (Bio)Chemistry: Identification and Mechanistic Classification.

Chembiochem : a European journal of chemical biology·2024
Same author

Bromide Ion Impurity-Induced Reaction between Selenium(IV) and Acidic Bromate: Prototype of a Cycle with Autocatalytic Behavior.

Inorganic chemistry·2024
Same author

Kinetics and Mechanism of Selenium(IV) Oxidation by Aqueous Bromine Solution.

ACS omega·2023
Same author

Compatible Kinetic Model for Quantitative Description of Dual-Clock Behavior of the Complex Thiourea-Iodate Reaction.

Inorganic chemistry·2023
Same author

Autoinhibition by Iodide Ion in the Methionine-Iodine Reaction.

The journal of physical chemistry. A·2020
Same author

Law of Mass Action Type Chemical Mechanisms for Modeling Autocatalysis and Hypercycles: Their Role in the Evolutionary Race.

Chemphyschem : a European journal of chemical physics and physical chemistry·2020

Related Experiment Video

Updated: Nov 12, 2025

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction
09:28

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Published on: August 31, 2018

7.5K

Correct classification and identification of autocatalysis.

Attila K Horváth1

  • 1Department of Inorganic Chemistry, Faculty of Sciences, University of Pécs, Pécs, Hungary. horvatha@gamma.ttk.pte.hu.

Physical Chemistry Chemical Physics : PCCP
|March 18, 2021
PubMed
Summary

Autocatalysis, a kinetic phenomenon where reaction products accelerate the reaction, is redefined. This study clarifies autocatalysis characterization and classification, emphasizing the necessary increase in autocatalyst concentration.

More Related Videos

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

585
Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

9.2K

Related Experiment Videos

Last Updated: Nov 12, 2025

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction
09:28

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Published on: August 31, 2018

7.5K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

585
Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

9.2K

Area of Science:

  • Chemical Kinetics
  • Biochemistry

Background:

  • Autocatalysis is a kinetic phenomenon where a reaction product acts as a catalyst.
  • Sigmoidal concentration-time profiles are often observed but are not definitive indicators of autocatalysis.

Purpose of the Study:

  • To systematically analyze mass action kinetic models that produce sigmoidal profiles.
  • To refine the definitions of autocatalysis and autocatalyst.
  • To clarify the characterization and classification of autocatalytic processes.

Main Methods:

  • Analysis of mass action kinetic models.
  • Systematic classification of kinetic phenomena.
  • Refinement of definitions based on mechanistic details.

Main Results:

  • Identified conditions for sigmoidal concentration-time profiles beyond simple autocatalysis.
  • Refined the definition of autocatalysis to include product-catalyzed subsystems or the whole system.
  • Established that autocatalyst concentration must increase during the reaction.

Conclusions:

  • Autocatalysis requires a product to catalyze at least one part of the reaction system.
  • The increase in autocatalyst concentration is a necessary feature of autocatalysis.
  • Mechanistic details are crucial for classifying autocatalytic processes.