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Intracerebral hemorrhage after kratom ingestion.

Glenna A Regan¹, Peter J Papadakos

¹Glenna A. Regan practices in the cardiac ICU at the University of Rochester (N.Y.) Medical Center. Peter J. Papadakos is a director of critical care medicine and a professor of anesthesiology, surgery, neurosurgery, and neurology at the University of Rochester Medical Center. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants

|March 18, 2021

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Kratom (Mitragyna speciosa), an herbal substance, is increasingly used but its adverse effects are unknown. This case study details a patient experiencing an intracerebral hemorrhage potentially linked to kratom consumption.

Area of Science:

Neurology
Toxicology
Pharmacology

Background:

Mitragyna speciosa, or kratom, is a tropical tree gaining popularity for its stimulant and opioid-like effects.
It is legally available in the US and marketed online as a safe opioid alternative.
Adverse reactions to kratom are not well-documented, posing a potential public health concern.

Purpose of the Study:

To report a case of intracerebral hemorrhage potentially associated with kratom ingestion.
To highlight the unknown risks of kratom use.

Main Methods:

Case report of a patient presenting with symptoms of intracerebral hemorrhage.
Review of patient history and substance use, including kratom.

Main Results:

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The patient experienced an intracerebral hemorrhage.
The hemorrhage was possibly secondary to kratom ingestion.

Conclusions:

Kratom ingestion may be associated with serious neurological adverse events such as intracerebral hemorrhage.
Further research is needed to understand the full spectrum of kratom's adverse effects and associated risks.