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Updated: Nov 12, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Embolic stroke of undetermined source (ESUS) - Classification of a new stroke entity]
Alkisti Kitsiou1, Frédéric Zuhorn1, Rolf Wachter2
1Evangelisches Klinikum Bethel, Klinik für Neurologie, Bielefeld, Deutschland.
Abstract:
Embolic stroke of undetermined source (ESUS) represents a subpopulation of cryptogenic strokes defined by its embolic stroke pattern on imaging and if after a carefully performed diagnostic evaluation, a specific, well recognized cause of stroke has not been identified. This review article analyses the basics of the ESUS concept and provides an overview of the evidence from recent cohort studies. The definition, aetiology and diagnosis of ESUS are reassessed. Targeted diagnostics in ESUS patients can reduce the number of cryptogenic strokes by making a specific diagnosis.
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