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Ureteral necrosis in dermatomyositis.
M Borrelli1, M J Prado, P Cordeiro
1Department of Urology, Hospital Das Clinicas, Medical School, University of São Paulo, Brazil.
The Journal of Urology
|June 1, 1988
Summary
Childhood dermatomyositis can cause calcified necrosis in the ureters. This vasculitis-related ureteral necrosis specifically affects the middle third due to reduced blood flow.
Area of Science:
- Pediatric Rheumatology
- Pediatric Nephrology
- Vascular Pathology
Background:
- Dermatomyositis is an autoimmune disease affecting muscles and skin.
- Ureteral complications are rare in pediatric rheumatological conditions.
- The middle third of the ureter is a watershed area with limited vascular supply.
Observation:
- A pediatric case presenting with dermatomyositis and bilateral ureteral calcification.
- Histopathology revealed vasculitis leading to ureteral necrosis and calcification.
- The affected ureteral segments were exclusively in the middle third.
Findings:
- Established a correlation between childhood dermatomyositis and ureteral necrosis.
- Identified vasculitis as the underlying pathological mechanism.
- Highlighted the predilection for the middle third of the ureter due to its unique vascular anatomy.
Implications:
- Suggests a need for increased vigilance for ureteral complications in children with dermatomyositis.
- Highlights the importance of considering vascular compromise in the middle ureter.
- Informs potential diagnostic and therapeutic strategies for this rare complication.