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Published on: January 18, 2022
Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues
Yan-Wei Li1,2, Leon Loh Yeong Wei1, Matteo Paoluzzi3
1Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Abstract:
Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.

