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Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

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Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
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Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives01:22

Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives

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Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This...
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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Related Experiment Video

Updated: Nov 12, 2025

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Published on: July 5, 2024

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Non-pharmacologic approach to pediatric constipation.

Neha R Santucci1, Ashish Chogle2, Alycia Leiby3

  • 1Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, OH, USA.

Complementary Therapies in Medicine
|March 19, 2021
PubMed
Summary

Non-pharmacologic treatments for pediatric functional constipation, including supplements and mind-body interventions, show promise. However, robust pediatric data is limited, necessitating further research for efficacy and safety.

Keywords:
FiberFunctional constipationIntegrative medicineTreatment

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Area of Science:

  • Pediatric Gastroenterology
  • Integrative Medicine
  • Nutritional Science

Background:

  • Functional constipation (FC) is a common pediatric issue.
  • Pharmaceuticals for FC face parental and patient reluctance.
  • Interest in over-the-counter nutraceuticals and botanicals for FC is growing.

Purpose of the Study:

  • To review research on non-pharmacologic constipation treatments in children.
  • To evaluate the safety and efficacy of these pediatric constipation modalities.

Main Methods:

  • Literature review of non-pharmacologic approaches for pediatric constipation.
  • Analysis of studies on supplements, botanicals, mind-body interventions, and movement therapies.

Main Results:

  • Data on pediatric non-pharmacologic treatments is sparse and often flawed.
  • Prebiotics, probiotics, and fiber supplements show safety and emerging evidence.
  • Mind-body and movement interventions are safe and show promise, requiring more study.

Conclusions:

  • Non-pharmacologic options like fiber, prebiotics, probiotics, mind-body, and movement therapies are viable for pediatric FC.
  • Further high-quality research is crucial to establish definitive efficacy and safety profiles for these pediatric interventions.