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Acute Lower Limb Ischemia in Patients Infected with COVID-19
Nabil Al-Zoubi1, Nawaf Shatnawi1, Hamza Jarbo1
1Department of General Surgery/Vascular Surgery, Jordan University of Science and Technology, Irbid, Jordan.
Insights
COVID-19 patients had a 0.54% prevalence of acute lower limb ischemia (ALLI). Patients with COVID-19 pneumonia who developed ALLI during hospitalization experienced high mortality rates.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Critical Care Medicine
Background:
- COVID-19 infection has been associated with various vascular complications.
- Acute lower limb ischemia (ALLI) is a serious condition that can occur in critically ill patients.
- Understanding the prevalence and outcomes of ALLI in COVID-19 patients is crucial for clinical management.
Purpose of the Study:
- To determine the prevalence of acute lower limb ischemia (ALLI) in patients with COVID-19.
- To analyze the characteristics of COVID-19 patients who develop ALLI.
- To evaluate the outcomes of ALLI in this patient population.
Main Methods:
- Retrospective review of patients admitted to King Abdullah University Hospital (KAUH) between November 1, 2020, and December 31, 2020.
- Identification of patients diagnosed with both ALLI and COVID-19 infection.
- Analysis of patient demographics, clinical presentation, treatment, and outcomes.
Main Results:
- Seven out of 1300 COVID-19 patients (0.54%) were diagnosed with ALLI.
- Male patients with COVID-19 pneumonia who developed ALLI during hospitalization had a high mortality rate (100% mortality within 24 hours).
- Female patients presenting with ALLI and subsequently diagnosed with COVID-19 had better outcomes, with no deaths but one case of amputation.
Conclusions:
- The prevalence of ALLI among hospitalized COVID-19 patients was found to be 0.54%.
- COVID-19 patients with pneumonia who develop ALLI during their hospital stay face a significantly high risk of mortality.
- Prompt diagnosis and management of ALLI in COVID-19 patients are critical, with outcomes potentially differing based on presentation and comorbidities.
Background:
The aim of this study was to investigate the prevalence of acute lower limb ischemia (ALLI) among patients infected with COVID-19 and to review their characteristics and outcomes.
Methods:
This study was performed at King Abdullah University Hospital (KAUH) in the north of Jordan. All patients with ALLI and COVID-19 infection, between November 1, 2020 and December 31, 2020, were retrospectively identified and reviewed.
Results:
A total number of 1300 COVID-19 patients were admitted to KAUH during the period of the study. Seven patients (0.54%) had ALLI. Of them, 5 were males (71.4%) with a mean age of 68 ± 3 years and 2 were females (28.6%) with a mean age of 58 ± 7 years. Five patients (71.4%) were admitted as COVID-19 infection and developed ALLI during hospitalization, all of them were males, had COVID-19 related pneumonia, and died within 24 hours of ALLI diagnosis. While 2 patients were presented with ALLI and found to have positive COVID-19, all of them were females, underwent successful thrombo-embolectomy, and had no deaths, however, one of them had recurrent ALLI which resulted in below knee amputation.
Conclusion:
The prevalence of ALLI in patients infected with COVID-19 was 0.54%. We observed that patients with COVID-19 related pneumonia who develop ALLI during hospitalization had a high mortality.
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