Acute Lower Limb Ischemia in Patients Infected with COVID-19

Nabil Al-Zoubi1, Nawaf Shatnawi1, Hamza Jarbo1

  • 1Department of General Surgery/Vascular Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Insights

COVID-19 patients had a 0.54% prevalence of acute lower limb ischemia (ALLI). Patients with COVID-19 pneumonia who developed ALLI during hospitalization experienced high mortality rates.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • COVID-19 infection has been associated with various vascular complications.
  • Acute lower limb ischemia (ALLI) is a serious condition that can occur in critically ill patients.
  • Understanding the prevalence and outcomes of ALLI in COVID-19 patients is crucial for clinical management.

Purpose of the Study:

  • To determine the prevalence of acute lower limb ischemia (ALLI) in patients with COVID-19.
  • To analyze the characteristics of COVID-19 patients who develop ALLI.
  • To evaluate the outcomes of ALLI in this patient population.

Main Methods:

  • Retrospective review of patients admitted to King Abdullah University Hospital (KAUH) between November 1, 2020, and December 31, 2020.
  • Identification of patients diagnosed with both ALLI and COVID-19 infection.
  • Analysis of patient demographics, clinical presentation, treatment, and outcomes.

Main Results:

  • Seven out of 1300 COVID-19 patients (0.54%) were diagnosed with ALLI.
  • Male patients with COVID-19 pneumonia who developed ALLI during hospitalization had a high mortality rate (100% mortality within 24 hours).
  • Female patients presenting with ALLI and subsequently diagnosed with COVID-19 had better outcomes, with no deaths but one case of amputation.

Conclusions:

  • The prevalence of ALLI among hospitalized COVID-19 patients was found to be 0.54%.
  • COVID-19 patients with pneumonia who develop ALLI during their hospital stay face a significantly high risk of mortality.
  • Prompt diagnosis and management of ALLI in COVID-19 patients are critical, with outcomes potentially differing based on presentation and comorbidities.
Abstract

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