Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacological Inhibition of SP1 Reverses Cancer Stemness and Enhances Sorafenib Efficacy in Hepatocellular Carcinoma.

Cells·2026
Same author

Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells.

Nature communications·2026
Same author

Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes.

iScience·2026
Same author

Anti-CD3 mAb treatment reshapes infiltrating T and β cells in the islets in autoimmune diabetes.

JCI insight·2026
Same author

The epigenetic regulator SETDB1 as a key component of cancer stem cells and drug resistance in primary liver cancer.

Cellular oncology (Dordrecht, Netherlands)·2026
Same author

Are All Alginate Dressings Equivalent?

Journal of biomedical materials research. Part B, Applied biomaterials·2025

Related Experiment Video

Updated: Nov 12, 2025

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
08:02

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Published on: January 7, 2019

11.3K

Post-decellularization techniques ameliorate cartilage decellularization process for tissue engineering applications.

Mahsa Nouri Barkestani1, Sina Naserian1,2,3, Georges Uzan1,4

  • 1INSERM UMR-S-MD 1197, Hôpital Paul Brousse, Villejuif, France.

Journal of Tissue Engineering
|March 19, 2021
PubMed
Summary
This summary is machine-generated.

Tissue engineering offers new hope for degenerative disorders by improving decellularized cartilage extracellular matrix (ECM) scaffolds. Post-decellularization methods enhance mechanical strength and bioactivity for better osteoarthritis treatment.

Keywords:
Cartilage tissue engineeringdecellularized extracellular matrixosteoarthritispost-decellularization

More Related Videos

Synthesis of Decellularized Cartilage Extracellular Matrix Hydrogels
08:34

Synthesis of Decellularized Cartilage Extracellular Matrix Hydrogels

Published on: July 21, 2023

1.3K
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
08:58

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

14.5K

Related Experiment Videos

Last Updated: Nov 12, 2025

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
08:02

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

Published on: January 7, 2019

11.3K
Synthesis of Decellularized Cartilage Extracellular Matrix Hydrogels
08:34

Synthesis of Decellularized Cartilage Extracellular Matrix Hydrogels

Published on: July 21, 2023

1.3K
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
08:58

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

14.5K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Materials Science

Background:

  • Tissue engineering (TE) is crucial for treating degenerative disorders due to limited therapeutic options.
  • TE involves decellularization and recellularization of tissues or cell functionalization of scaffolds.
  • Conventional TE steps have advanced significantly in recent years.

Purpose of the Study:

  • To review advancements in tissue engineering for degenerative disorders.
  • To focus on novel post-decellularization methods for cartilage extracellular matrix (ECM).
  • To enhance decellularized ECM scaffolds for osteoarthritis (OA) treatment.

Main Methods:

  • Review of conventional tissue engineering processes.
  • Analysis of novel post-decellularization techniques for cartilage ECM.
  • Proposal of procedures to improve scaffold properties.

Main Results:

  • Conventional TE methods have shown considerable progress.
  • Post-decellularization strategies can significantly improve decellularized cartilage ECM efficiency.
  • Proposed methods address limitations like low mechanical strength and poor bioactivity.

Conclusions:

  • Tissue engineering holds promise for degenerative disorder treatment.
  • Post-decellularization offers a pathway to enhance decellularized ECM scaffolds.
  • Improved scaffolds can lead to more efficient integration and better OA treatment outcomes.