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Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

813
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
813
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

414
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
414
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

423
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
423
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

199
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
199
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

118
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
118
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

170
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
170

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Related Experiment Video

Updated: Nov 12, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

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Levofloxacin-Induced Acute Pancreatitis.

Tiago Neto Gonçalves1, Débora Sousa1, Natália Marto1

  • 1Internal Medicine Department, Hospital da Luz Lisboa, Lisbon, PRT.

Cureus
|March 19, 2021
PubMed
Summary

Levofloxacin (LVF), an antibiotic, can rarely cause acute pancreatitis (AP). This case highlights the importance of considering LVF as a potential cause of AP in patients presenting with abdominal pain and elevated pancreatic enzymes.

Keywords:
adverse reactionantibioticlevofloxacinpancreatitisquinoloneside effect

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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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Area of Science:

  • Internal Medicine
  • Gastroenterology
  • Pharmacology

Background:

  • Drug-induced pancreatitis is a rare cause of acute pancreatitis (AP), accounting for less than 2% of cases.
  • Quinolones are frequently prescribed antimicrobials, with sporadic reports linking them to pancreatitis.

Observation:

  • A 74-year-old male developed fever, severe abdominal pain, and nausea two days after starting levofloxacin (LVF) for acute cystitis.
  • Initial laboratory tests showed leukocytosis, elevated C-reactive protein, amylase, and lipase.
  • Abdominal ultrasound revealed pancreatic head inflammation consistent with AP.

Findings:

  • The patient was diagnosed with acute pancreatitis.
  • Discontinuation of levofloxacin and supportive care led to complete symptom resolution.
  • No other causes for acute pancreatitis were identified.

Implications:

  • Levofloxacin-induced pancreatitis, though uncommon, should be considered in patients with acute pancreatitis.
  • Enhanced physician awareness is crucial for the timely diagnosis and management of this adverse drug reaction.