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Updated: Nov 12, 2025
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
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Recent advancements in melanoma management
Tharani Krishnan1, Alexander M Menzies2,3, Rachel Roberts-Thomson1
1Medical Oncology Department, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.
Internal Medicine Journal
|March 19, 2021
Summary
Recent advances in targeted therapy and immunotherapy have significantly improved outcomes for advanced melanoma patients. These innovative treatments are now also used as adjuvant therapy for earlier-stage melanoma following surgery.
Area of Science:
- Oncology
- Dermatology
- Cancer Research
Background:
- Melanoma treatment landscape has evolved rapidly.
- Targeted therapy and immunotherapy have revolutionized advanced melanoma care.
- Adjuvant therapy is increasingly used for earlier-stage melanoma post-surgery.
Purpose of the Study:
- To review the latest advancements in melanoma treatment.
- To provide an update on melanoma staging, surgical resection, radiotherapy, and systemic therapies.
- To highlight the impact of novel therapies on patient outcomes.
Main Methods:
- Literature review of recent studies and clinical trials.
- Analysis of updated melanoma staging guidelines.
- Synthesis of current practices in surgical resection and radiotherapy.
- Evaluation of systemic therapy options, including targeted therapy and immunotherapy.
Main Results:
- Significant expansion of treatment options for melanoma.
- Dramatic improvement in prognosis for advanced melanoma with targeted therapy and immunotherapy.
- Successful application of these therapies as adjuvant treatment for early-stage melanoma.
- Comprehensive overview of current melanoma management strategies.
Conclusions:
- Targeted therapy and immunotherapy represent major breakthroughs in melanoma treatment.
- Adjuvant use of these novel therapies offers new hope for earlier-stage patients.
- Updated staging and multimodal treatment approaches are crucial for optimal melanoma care.
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