Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nucleic Acid Structure01:25

Nucleic Acid Structure

7.8K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
7.8K
Conjugation01:19

Conjugation

1.4K
Conjugation is a form of horizontal gene transfer that primarily occurs in bacteria and some archaea, promoting genetic diversity and adaptation. Bacteria can acquire resistance genes through conjugative plasmids, allowing them to survive antibiotic treatments that would otherwise be lethal. This process involves direct contact between cells through specialized structures such as the sex pilus and is mediated by conjugative plasmids, including the F (fertility) factor.Conjugation requires...
1.4K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

15.8K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
15.8K
DNA Bacteriophages01:26

DNA Bacteriophages

373
Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
373
Complementary DNA01:44

Complementary DNA

30.3K
Overview
30.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polydopamine-polyethylene glycol-liproxstatin-1 nanoparticles inhibit ferroptosis for enhanced treatment of neutrophilic asthma.

Frontiers in pharmacology·2026
Same author

Reversible Nucleolar Complex Coacervation by Short Cationic Peptides.

Journal of the American Chemical Society·2026
Same author

Improving the Activity of Phi29 DNA Polymerase by SaProt Prediction.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Bottom-up synthesis of molecular nanodiamond from nanographene.

Nature·2026
Same author

Mimicking a Light-Harvesting Complex to Accelerate Photooxidation in Asymmetric Lipid Membrane Nanoreactors.

Angewandte Chemie (International ed. in English)·2026
Same author

I<sub>2</sub>-mediated oxidative dearomatization for the synthesis of spirooxindole-lactones in water.

Chemical communications (Cambridge, England)·2026
Same journal

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026
Same journal

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026
Same journal

Ink Design for Printing Perovskite Solar Cells and Modules.

Chemical reviews·2026
Same journal

Advanced Single-Atom Catalysts for Thermal-Catalytic C1 Chemistry.

Chemical reviews·2026
Same journal

Copper-Dependent Polysaccharide Monooxygenases: Mechanism and Function.

Chemical reviews·2026
Same journal

To Biotic or Abiotic: Biohybrid Systems for Artificial Photosynthesis.

Chemical reviews·2026
See all related articles

Related Experiment Video

Updated: Nov 12, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.5K

Functional DNA-Polymer Conjugates.

Colette J Whitfield1, Meizhou Zhang2, Pia Winterwerber1

  • 1Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany.

Chemical Reviews
|March 19, 2021
PubMed
Summary
This summary is machine-generated.

DNA-polymer conjugates combine DNA nanotechnology and polymer science for advanced nanostructures. These materials offer stimuli-responsiveness for applications like drug delivery.

More Related Videos

Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

19.5K
Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

982

Related Experiment Videos

Last Updated: Nov 12, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.5K
Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

19.5K
Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

982

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Polymer Chemistry

Background:

  • DNA nanotechnology has advanced significantly due to solid-phase synthesis and DNA nanostructure discovery.
  • Polymer science offers diverse polymerization methods for creating block copolymers with tunable properties.
  • The integration of DNA and polymer science enables the creation of novel hybrid materials.

Purpose of the Study:

  • To review the progress of DNA-polymer conjugates.
  • To explore synthetic routes for creating these conjugates.
  • To highlight state-of-the-art applications, particularly in biomedical fields.

Main Methods:

  • Utilizing solid-phase synthesis for DNA component.
  • Employing various polymerization approaches for polymer component.
  • Synthesizing amphiphilic DNA-polymer conjugates.

Main Results:

  • Successful creation of DNA-polymer conjugates with tunable properties.
  • Development of nanostructures like micelles from these conjugates.
  • Incorporation of stimuli-responsiveness (pH, temperature, DNA binding) into nanostructures.

Conclusions:

  • DNA-polymer conjugates represent a powerful platform for advanced nanomedicine.
  • These conjugates offer versatile design possibilities for targeted drug delivery.
  • Further research in this interdisciplinary field holds significant promise.