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Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic

Yue-Ping Li1, Qing-Ting Bu1, Ji-Feng Li1

  • 1First Affiliated Hospital and Institute of Pharmaceutical Biotechnology, Zhejiang University School of Medicine, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory for Microbial Biochemistry and Metabolic Engineering, Hangzhou 310058, China.

Bioresource Technology
|March 20, 2021
PubMed

Keywords:
Combinatorial engineering strategyFidaxomicinGenetic stabilityMulti-copyStrain improvement

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