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Updated: Nov 12, 2025
06:23
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
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Brucellosis in transplant recipients: A systematic review
Mohammad M Rabiei1,2, Fariba Imanzade1,2, Firouze Hatami1,2
1Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Summary
Brucellosis is rare in transplant patients but can occur. Early and late onset disease is possible, emphasizing the need for careful screening and monitoring post-transplant to prevent this bacterial infection.
Area of Science:
- Infectious Diseases
- Transplantation Medicine
- Microbiology
Background:
- Brucellosis is a bacterial infection caused by Brucella species.
- Transplant recipients are a vulnerable population for opportunistic infections.
Purpose of the Study:
- To evaluate the incidence and characteristics of brucellosis in patients who have undergone organ or stem cell transplantation.
Main Methods:
- A comprehensive literature search was conducted across multiple databases for cases of brucellosis in transplant patients.
- Clinical features, transmission timing, treatment, and outcomes were analyzed from retrieved case reports and studies.
Main Results:
- Fourteen cases of brucellosis in transplant recipients were identified from 777 studies.
- Kidney, liver, and hematopoietic stem cell transplants were the most common types.
- Brucellosis presented in both early (42.8%) and late (57.1%) post-transplantation periods.
Conclusions:
- Brucellosis is an uncommon complication in transplant recipients, even in endemic areas.
- Transmission can occur via transplantation or transfusion, highlighting the importance of donor screening.
- Vigilant monitoring and management are crucial to reduce brucellosis incidence in this patient group.
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