Related Experiment Video
Updated: Nov 12, 2025

07:22
Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
11.7K
Effects of refractive power on quantification using ultra-widefield retinal imaging
Su-Ho Lim1,2, Seongyong Jeong2,3, Jang Hwan Ahn2,3
1Department of Ophthalmology, Daegu Veterans Health Service Medical Center, Daegu, Korea.
BMC Ophthalmology
|March 21, 2021
Summary
Refractive error can alter retinal area measurements in ultra-widefield (UWF) imaging, especially in longer eyes. Ophthalmologists should account for refractive error when quantifying retinal areas in these patients.
Area of Science:
- Ophthalmology
- Medical Imaging
- Optometry
Background:
- Ultra-widefield (UWF) retinal imaging is prone to distortion upon 2D projection.
- Stereographic projection algorithms are used to map 3D fundus images to 2D planes.
- Refractive error may theoretically impact the size and quality of UWF retinal images.
Purpose of the Study:
- To investigate the impact of refractive power on retinal area measurements using UWF imaging.
- To assess the influence of refractive error on quantitative analysis of retinal images.
Main Methods:
- Prospective study involving 50 healthy eyes.
- UWF images acquired with and without various soft contact lenses (CLs) (-9D to +9D).
- Stereographic projection used for optic disc quantification; subjects grouped by axial length (A: 22-24mm, B: 24-26mm, C: ≥26mm).
Main Results:
- No significant overall changes in measured retinal area across the entire study population.
- Group C (long axial length) showed a higher proportion of magnification effects (50%) compared to Groups A and B (P=0.020).
- Measured area was significantly higher in Group C with plus lenses (P<0.001).
Conclusions:
- Contact lens use can affect retinal area quantification in eyes with long axial lengths using UWF imaging.
- Refractive error should be considered during area measurements in long eyes with UWF imaging.

