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A Clinically Applicable Prediction Model for the Risk of Transfusion in Women Undergoing Myomectomy
Jordan S Klebanoff1, Cherie Q Marfori2, Andrew D Sparks3
1Department of Obstetrics and Gynecology, Main Line Health (Dr. Klebanoff), Wynnewood, Pennsylvania.
Journal of Minimally Invasive Gynecology
|March 21, 2021
Summary
Black race, preoperative transfusion needs, abdominal surgery, and low hematocrit are key predictors for blood transfusion during myomectomy. This helps predict and manage transfusion risk in women undergoing the procedure.
Area of Science:
- Gynecology
- Surgical Oncology
- Hematology
Background:
- Myomectomy is a common procedure for uterine fibroids.
- Blood transfusion during myomectomy can lead to complications.
- Predicting transfusion risk is crucial for patient safety.
Purpose of the Study:
- Identify factors associated with intra/postoperative blood transfusion during myomectomy.
- Develop a predictive model for transfusion risk using preoperative variables.
Main Methods:
- Retrospective case-control study using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database.
- Analysis of 6387 myomectomies performed between 2014 and 2017.
- Multivariable logistic regression to identify predictors and develop a risk model.
Main Results:
- 9.8% of patients (623/6387) required blood transfusion.
- Independent predictors for transfusion included Black race, prior blood transfusion, planned abdominal/open surgery, and lower preoperative hematocrit.
- A predictive model was developed using these preoperative variables.
Conclusions:
- Several perioperative variables are associated with the need for blood transfusion during myomectomy.
- A validated model can accurately predict individual bleeding risk preoperatively.
- Clinical availability of this model can improve patient care during myomectomy.

