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Published on: January 5, 2017
Immunoinflammatory effects of dietary bioactive compounds
Francesca Giampieri1, Danila Cianciosi2, Johura Ansary2
1Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Sez. Biochimica, Università Politecnica delle Marche, Ancona, Italy; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Dietary bioactive compounds modulate immune responses. This review summarizes how micronutrients, omega-3 fatty acids, nucleotides, and polyphenols impact inflammation, potentially preventing chronic inflammatory diseases.
Area of Science:
- Immunology and Nutritional Science
Background:
- Inflammation is a critical immune response to harmful stimuli.
- Uncontrolled inflammation can lead to chronic conditions and tissue damage.
- Diet is a significant factor influencing chronic inflammation.
Purpose of the Study:
- To summarize the effects of dietary bioactive compounds on immunoinflammatory responses.
- To review findings from cellular, animal, and human studies.
Main Methods:
- Literature review of studies on dietary bioactive compounds and inflammation.
- Analysis of effects on immune signaling pathways and cells.
Main Results:
- Micronutrients, omega-3 fatty acids, nucleotides, and polyphenols exhibit immunomodulatory effects.
- These compounds influence inflammatory pathways in various experimental models.
- Evidence suggests a role in managing inflammatory status.
Conclusions:
- Dietary bioactive compounds represent a promising area for managing inflammatory responses.
- Further research can elucidate mechanisms and therapeutic potential for chronic inflammation.
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