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Updated: Nov 12, 2025

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Identifying and Understanding Transfusion Reactions in the Oncology Population
Carrie A Graham1, Danielle DuBois1, Christine Gleason1
1Division of Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA.
Objectives:
To provide an overview of transfusion reactions, their underlying pathophysiology, clinical presentation, and recommendations for nursing management.
Data Sources:
We researched peer-reviewed journal articles, book chapters, Internet, and lecture proceedings.
Conclusion:
Transfusion reactions are adverse reactions to blood products frequently seen in the oncology population and can significantly vary in severity and etiology. Oncology nurses are in a critical position to assist with prevention, early detection, and time-sensitive treatment of transfusion reactions.
Implications For Nursing Practice:
The oncology nurse's comprehensive understanding of possible transfusion reactions and management recommendations is key for optimal care of the oncology patient.
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