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Updated: Nov 12, 2025
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Brain lymphoma development related to a long lasting epidermoid cyst
Angel Horcajadas Almansa1, Ana M Jorques Infante1, Clara E Chamorro Santos2
1Servicio de Neurocirugía. Hospital Virgen de las Nieves. Granada. España.
Introduction:
Epidermoid cysts (EC) are benign and slow growing lesions. A primary brain lymphoma development related to a EC is presented, second case described in literature.
Case Presentation:
A woman 40 years old, harbouring a EC for more than 20 years, develops a fast growing brain lesion next to the EC. Surgery was performed and diagnosis was primary diffuse B cells lymphoma.
Discussion:
Malignant transformation of EC has been described, usually to squamous cells carcinoma, and much less frequently, to another tumours. Inflammatory mechanisms have been advocated to explain this evolution. Chronic inflammation and lymphoma genesis are related, and this could be the mechanism behind this rare evolution of an EC.
Conclusions:
Even being benign lesions, EC can develop malignant tumours due to the chronic inflammation secondary to them.
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