Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Associative Learning01:27

Associative Learning

830
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
830
Protein Networks02:26

Protein Networks

4.3K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.3K
Protein Networks02:26

Protein Networks

2.6K
2.6K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

14.9K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
14.9K
Real-World Application of Classical Conditioning01:15

Real-World Application of Classical Conditioning

913
Classical conditioning not only includes the initial pairing of stimuli but also extends to more complex forms, such as higher-order conditioning. Higher-order conditioning involves creating associations beyond the primary conditioned stimulus, resulting in a chain of conditioned responses.
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
913
Sequence Networks of Rotating Machines01:24

Sequence Networks of Rotating Machines

346
A Y-connected synchronous generator, grounded through a neutral impedance, is designed to produce balanced internal phase voltages with only positive-sequence components. The generator's sequence networks include a source voltage that is exclusively in the positive-sequence network. The sequence components of line-to-ground voltages at the generator terminals illustrate this configuration.
Zero-sequence current induces a voltage drop across the generator's neutral impedance and other...
346

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Dimensional Knockoffs Inference for Time Series Data.

Journal of the American Statistical Association·2025
Same author

DeepDeconUQ estimates malignant cell fraction prediction intervals in bulk RNA-seq tissue.

PLoS computational biology·2025
Same author

Optimal Nonparametric Inference with Two-Scale Distributional Nearest Neighbors.

Journal of the American Statistical Association·2024
Same author

Asymptotic Theory of Eigenvectors for Random Matrices with Diverging Spikes.

Journal of the American Statistical Association·2022
Same author

ASYMPTOTIC DISTRIBUTIONS OF HIGH-DIMENSIONAL DISTANCE CORRELATION INFERENCE.

Annals of statistics·2021
Same author

DeepLINK: Deep learning inference using knockoffs with applications to genomics.

Proceedings of the National Academy of Sciences of the United States of America·2021
Same journal

Gradient Descent Provably Solves Nonlinear Tomographic Reconstruction.

IEEE transactions on information theory·2026
Same journal

Theoretical Guarantees for Sparse Principal Component Analysis based on the Elastic Net.

IEEE transactions on information theory·2025
Same journal

Uniform Convergence of Deep Neural Networks With Lipschitz Continuous Activation Functions and Variable Widths.

IEEE transactions on information theory·2025
Same journal

Kernel Stein Discrepancy on Lie Groups: Theory and Applications.

IEEE transactions on information theory·2024
Same journal

Matrix Reordering for Noisy Disordered Matrices: Optimality and Computationally Efficient Algorithms.

IEEE transactions on information theory·2024
Same journal

Non-Asymptotic Guarantees for Reliable Identification of Granger Causality via the LASSO.

IEEE transactions on information theory·2024
See all related articles

Related Experiment Video

Updated: Nov 12, 2025

Automatic Identification of Dendritic Branches and their Orientation
06:08

Automatic Identification of Dendritic Branches and their Orientation

Published on: September 17, 2021

2.1K

SOFAR: Large-Scale Association Network Learning.

Yoshimasa Uematsu1, Yingying Fan1, Kun Chen1

  • 1Yoshimasa Uematsu is Assistant Professor, Department of Economics and Management, Tohoku University, Sendai 980-8576, Japan. Yingying Fan is Dean's Associate Professor in Business Administration, Data Sciences and Operations Department, Marshall School of Business, University of Southern California, Los Angeles, CA 90089. Kun Chen is Associate Professor, Department of Statistics, University of Connecticut, Storrs, CT 06269. Jinchi Lv is Kenneth King Stonier Chair in Business Administration and Professor, Data Sciences and Operations Department, Marshall School of Business, University of Southern California, Los Angeles, CA 90089. Wei Lin is Assistant Professor, School of Mathematical Sciences and Center for Statistical Science, Peking University, Beijing, China 100871.

IEEE Transactions on Information Theory
|March 22, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces sparse orthogonal factor regression (SOFAR), a novel method for analyzing large-scale data networks. SOFAR effectively balances sparsity and orthogonality, enhancing statistical efficiency and scientific insights in big data applications.

Keywords:
Big dataLarge-scale association networkLatent factorsNonconvex statistical learningOrthogonality constrained optimizationSimultaneous response and predictor selectionSparse singular value decomposition

More Related Videos

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.6K
Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
08:27

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

4.5K

Related Experiment Videos

Last Updated: Nov 12, 2025

Automatic Identification of Dendritic Branches and their Orientation
06:08

Automatic Identification of Dendritic Branches and their Orientation

Published on: September 17, 2021

2.1K
Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
09:49

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

4.6K
Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
08:27

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

4.5K

Area of Science:

  • Statistics
  • Machine Learning
  • Data Mining

Background:

  • Modern big data applications involve numerous responses and predictors, necessitating advanced analytical techniques.
  • Understanding large-scale association networks through sparse latent factors is crucial for statistical efficiency and scientific discovery.
  • Achieving both sparsity and orthogonality in factor analysis has been a significant challenge.

Purpose of the Study:

  • To propose a novel method, sparse orthogonal factor regression (SOFAR), that accommodates both sparsity and orthogonality in analyzing large-scale data.
  • To develop a robust framework for learning underlying association networks in big data.
  • To provide theoretical guarantees and demonstrate practical utility across various machine learning tasks.

Main Methods:

  • SOFAR utilizes sparse singular value decomposition with orthogonality-constrained optimization.
  • The method employs convexity-assisted non-convex optimization techniques.
  • Non-asymptotic error bounds are derived to characterize theoretical advantages.

Main Results:

  • The proposed SOFAR method effectively integrates sparsity and orthogonality.
  • Theoretical analysis provides non-asymptotic error bounds, demonstrating statistical guarantees.
  • An efficient SOFAR algorithm with proven convergence properties is presented.

Conclusions:

  • SOFAR offers a powerful approach for uncovering latent structures in large-scale datasets.
  • The method demonstrates broad applicability in both unsupervised and supervised learning, including biclustering and sparse factor analysis.
  • Simulations and real-world examples validate the computational and theoretical advantages of SOFAR.