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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

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Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis.

Abdallah Abboud1, Karim Masrouha2, Maelle Saliba3

  • 1Division of Orthopedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut 1013, Lebanon.

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|March 22, 2021
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Summary

Extraskeletal Ewing sarcoma (EES) is a rare soft tissue tumor. This review details EES diagnosis, management, and prognosis, highlighting subtype differences and optimal treatment needs.

Keywords:
Ewing sarcomadiagnosisprognosistherapy

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Extraskeletal Ewing sarcoma (EES) is a rare soft tissue malignancy, comprising 20-30% of Ewing sarcoma (ES) cases.
  • EES shares treatment protocols with other Ewing sarcoma family tumors due to its rarity.

Purpose of the Study:

  • To review the diagnosis, management, and prognosis of EES.
  • To highlight differences among EES subtypes.
  • To discuss clinical features and imaging characteristics of EES.

Main Methods:

  • Literature review summarizing current knowledge on EES.
  • Discussion of diagnostic modalities, including Magnetic Resonance Imaging (MRI) for staging.
  • Emphasis on core-needle biopsy for definitive pathological diagnosis.

Main Results:

  • MRI is the preferred imaging modality for diagnosis and local staging of EES.
  • Core-needle biopsy is essential for accurate pathological diagnosis.
  • While ES family tumors generally follow similar treatment protocols, local control strategies like surgery and radiotherapy are being investigated for EES.

Conclusions:

  • Optimal treatment strategies for EES require further investigation.
  • Understanding EES subtypes is crucial for tailored management.
  • Continued research is needed to define the best therapeutic algorithms for EES.