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MRI restoration using edge-guided adversarial learning.

Yaqiong Chai1,2, Botian Xu1, Kangning Zhang3

  • 1Department of Biomedical Engineering, University of Southern California, CA, USA.

IEEE Access : Practical Innovations, Open Solutions
|March 22, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces an edge-guided generative adversarial network (GAN) to restore missing slices and artifacts in 2D brain MRI scans. The novel method improves image quality for 3D reconstruction and comparative studies.

Keywords:
artifact correctionedgegenerative adversarial networkimage restorationimputationmagnetic resonance imaging

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Neuroscience

Background:

  • Multislice 2D MRI data present challenges for 3D reconstruction due to sparse through-plane sampling.
  • Image imputation techniques are crucial for restoring missing data or correcting artifacts in MRI scans.

Purpose of the Study:

  • To develop an edge-guided generative adversarial network (GAN) for restoring missing through-plane slices and artifacts in brain MRI images.
  • To enhance the utility of 2D MRI scans for 3D applications and large-scale brain morphometry studies.

Main Methods:

  • Proposed an edge-guided GAN inspired by image inpainting, decoupling restoration into edge connection and contrast completion stages.
  • Trained and tested the network on Human Connectome Project data for thick slice imputation and on clinical/simulated data for artifact correction.

Main Results:

  • The Edge-Guided GAN demonstrated superior performance in Peak Signal-to-Noise Ratio (PSNR), Structural Similarity Index Measure (SSIM), conspicuity, and signal texture.
  • Outperformed traditional imputation tools like Context Encoder and Densely Connected Super Resolution Network with GAN (DCSRN-GAN).

Conclusions:

  • The proposed GAN effectively restores damaged brain MRI images, addressing limitations of 2D acquisition.
  • This method can enhance the utilization of clinical 2D MRI scans for generating 3D atlases and conducting big-data comparative morphometry studies.