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Hairpin-Spacer crRNA-Enhanced CRISPR/Cas13a System Promotes the Specificity of Single Nucleotide Polymorphism (SNP)

Yuqing Ke1, Shiyi Huang1, Behafarid Ghalandari1

  • 1State Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200030 China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|March 22, 2021
PubMed

Keywords:
CRISPR/Cas13a systemGibbs free energycrRNA designhairpin structuressingle nucleotide polymorphisms

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