Related Experiment Video
Updated: Nov 12, 2025
06:07
Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
Published on: June 13, 2020
6.9K
Postbiotics as Promising Tools for Cancer Adjuvant Therapy
Aziz Homayouni Rad1, Leili Aghebati Maleki2, Hossein Samadi Kafil3
1Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Advanced Pharmaceutical Bulletin
|March 22, 2021
Summary
Postbiotics, derived from fermented foods and lactic acid bacteria (LAB), offer health benefits. These compounds show promise in cancer treatment by reducing side effects and enhancing therapy effectiveness.
Area of Science:
- Microbiology and Human Health
- Nutritional Science
- Oncology
Background:
- Fermented foods, lactic acid bacteria (LAB), and human health share a complex relationship mediated by bioactive components.
- Prebiotics and probiotics contribute to LAB activity, leading to the production of postbiotics.
Discussion:
- Postbiotics are micro- and macromolecules from fermented foods that promote host health.
- They possess anti-proliferative, anti-inflammatory, and anti-cancer properties.
- Postbiotics can moderate cancer treatment effectiveness and reduce therapy side-effects.
Key Insights:
- Postbiotics are key mediators in the fermented food-LAB-human health axis.
- Their biological and physiological properties are crucial for health promotion.
- Scientific attention is growing due to their potential in cancer adjuvant therapy.
Outlook:
- Further research into postbiotic mechanisms and applications in oncology is warranted.
- Exploring diverse sources and optimizing production of postbiotics for therapeutic use.
- Investigating the synergistic effects of postbiotics with conventional cancer treatments.
More Related Videos
06:06Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
2.8K
15:04Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
12.5K
Related Concept Videos
01:30Cancer Vaccines
610
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
610
01:27Tumor Immunotherapy
820
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
820
01:29Microorganisms in Medicine and Therapeutics
627
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
627
02:57Targeted Cancer Therapies
8.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.1K
01:15Drugs that Stabilize Microtubules
2.3K
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
2.3K
02:49Cancer Therapies
8.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.9K