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Related Experiment Video

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Design and Construction of a Cost Effective Headstage for Simultaneous Neural Stimulation and Recording in the Water Maze
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A Chopper-Stabilized, Current Feedback, Neural Recording Amplifier.

Aria Samiei1, Hossein Hashemi1

  • 1Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA 90089 USA.

IEEE Solid-State Circuits Letters
|March 22, 2021
PubMed
Summary

This study introduces a novel chopper-stabilized amplifier that boosts input impedance to 3.0 GΩ, overcoming limitations in neural prosthetics for improved signal recording and reduced tissue current draw.

Keywords:
Chopper-stabilizedhigh input impedancelow-noiselow-powerneural recording amplifier

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Electrical Engineering

Background:

  • Advanced neural prosthetics demand high-density electrodes for tissue interfacing.
  • Key implantable device metrics include area, power consumption, and noise performance.
  • Chopping techniques are essential for low-frequency neural signals but reduce input impedance.

Purpose of the Study:

  • To present a chopper-stabilized current feedback amplifier (CFA) designed to overcome the input impedance drop caused by chopping.
  • To achieve high input impedance for improved neural signal recording and reduced tissue current draw in neural prosthetics.

Main Methods:

  • Developed a chopper-stabilized current feedback amplifier (CFA).
  • Implemented techniques to boost amplifier input impedance.
  • Characterized amplifier performance including gain, cut-off frequency, power consumption, and noise efficiency factor (NEF).

Main Results:

  • Achieved a boosted input impedance of 3.0 GΩ.
  • The amplifier offers adjustable voltage gain (40-60 dB) and high-pass cut-off frequency (0.5-5 Hz).
  • Demonstrated low power consumption (2.6 μW) and a low noise efficiency factor (NEF) of 3.2.

Conclusions:

  • The developed CFA effectively addresses the input impedance limitations of chopping techniques in neural recording amplifiers.
  • This high-impedance amplifier design is suitable for advanced neural prosthetics, enhancing signal fidelity and reducing tissue interaction.
  • The design balances crucial metrics like area, power, and noise performance for implantable neural devices.