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Treating Acute Decompensated Heart Failure in Patients with COVID-19 Using Intravenous Nitroglycerin in 5%
Wayne Kaesemeyer1, Tatsiana Suvorava2
1Augusta Hypertension PC, 108 Tharrington Drive, Chapel Hill, NC, USA. kaehtn007@yahoo.com.
Insights
This article presents a new treatment for acute decompensated heart failure (ADHF) in COVID-19 patients. It uses a novel intravenous nitroglycerin formulation with glutathione to speed recovery and lower complication risks.
Area of Science:
- Cardiology
- Infectious Diseases
- Pharmacology
Background:
- Coronavirus disease 2019 (COVID-19) can lead to acute decompensated heart failure (ADHF).
- Standard treatments for ADHF may have limitations in COVID-19 patients.
Purpose of the Study:
- To introduce a novel therapeutic approach for ADHF in COVID-19 patients.
- To describe a new formulation of intravenous nitroglycerin using 5% glutathione.
Main Methods:
- This is a current opinion article, outlining a proposed treatment strategy.
- The proposed method involves the novel use of intravenous nitroglycerin reformulated in 5% glutathione.
Main Results:
- The novel formulation is hypothesized to improve the resolution rate of ADHF.
- It is also expected to reduce the risk of heart failure complications in COVID-19 patients.
Conclusions:
- This novel approach offers a potential advancement in managing ADHF in the context of COVID-19.
- Further investigation and clinical trials are warranted to validate the efficacy and safety of this new formulation.
Abstract:
The purpose of this current opinion article is to illustrate a novel approach to the treatment of acute decompensated heart failure (ADHF) in coronavirus disease 2019 (COVID-19) patients. The approach described herein relies on a reformulation of intravenous nitroglycerin in 5% glutathione, itself novel, and is felt to have the potential to not only improve the rate of resolution of ADHF, but also reduce the risk of complications of heart failure seen in patients with COVID-19.
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