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Updated: Nov 12, 2025
07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
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[ALLERGY PREVENTION AND TREATMENT DURING THE FIRST YEAR]
Ron Shaoul1, Miri Pevzner2, Zehavit Goldshtein3
1Pediatric Gastroenterology Institute, Ruth Children's Hospital, Rambam Medical Center., Faculty of Medicine, Technion.
Harefuah
|March 22, 2021
Summary
Exclusive breastfeeding for six months is recommended for infant allergy prevention. For non-breastfed infants at risk, hydrolyzed formulas may reduce allergy risk, while soy formulas are not recommended. Early introduction of solids is advised.
Area of Science:
- Pediatrics
- Allergology
- Immunology
Background:
- Maternal and infant nutrition significantly impacts allergy development.
- Recent research guides infant feeding recommendations for allergy prevention.
- Established guidelines exist for at-risk infants, including those with a family history of allergies.
Purpose of the Study:
- To summarize current evidence-based recommendations for infant feeding and allergy prevention.
- To inform healthcare professionals on managing infant nutrition for atopic disease risk.
- To highlight changes in clinical practice regarding infant feeding and allergen exposure.
Main Methods:
- Review of recent scientific literature and clinical guidelines.
- Analysis of recommendations from European and United States healthcare bodies.
- Synthesis of data on breastfeeding, hydrolyzed formulas, soy formulas, and solid food introduction.
Main Results:
- Exclusive breastfeeding for 6 months is recommended for all infants.
- Partially or fully hydrolyzed formulas may benefit non-breastfed infants at high risk of allergies.
- Early introduction of solids (4-6 months) without allergen avoidance is recommended; delayed introduction may increase allergy risk.
Conclusions:
- Current guidelines emphasize exclusive breastfeeding and early introduction of diverse solids.
- Hydrolyzed formulas are a viable option for specific high-risk, non-breastfed infants.
- Healthcare providers must stay updated on evolving infant nutrition and allergy prevention strategies.
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