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Updated: Nov 12, 2025

Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
[Germinoma in a patient with emaciation and growth retardation. Case report]
Antonella Y Ciucio1, Norma Schenone2
1Residencia de Clínica Pediátrica, Comité de Docencia e Investigación, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina. antonellayciucio@gmail.com.
Abstract:
Central nervous system tumors are the second most frequent oncological disease among children and teenagers. Among the intracranial tumors, the germ cells ones are infrequent. The symptoms they cause are headaches, nausea and vomiting, hormonal deficits, visual disturbances, weight loss, poor growth and early puberty. Less frequently, they produce movement or psychiatric disorders. Some of these tumors can be asymptomatic for a long period leading to a late diagnosis. The case of a 14-year-old female patient is presented. She showed weight loss and growth failure, with wrong diagnosis of eating disorder. After proper study methods, we arrived to central nervous system germinoma diagnosis. Because this pathology is rare and has a variable form of presentation, it requires that the family involved and the health team to be alert, to avoid delays in diagnosis and treatment.
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