Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

164
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
164
Routh-Hurwitz Criterion II01:19

Routh-Hurwitz Criterion II

595
In the application of the Routh-Hurwitz criterion, two specific scenarios can arise that complicate stability analysis.
The first scenario occurs when a singular zero appears in the first column of the Routh table. This situation creates a division by zero issues. To resolve this, a small positive or negative number, denoted as epsilon (∈), is substituted for the zero. The stability analysis proceeds by assuming a sign for ∈. If ∈ is positive, any sign change in the first...
595
Response Surface Methodology01:16

Response Surface Methodology

379
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
379
Routh-Hurwitz Criterion I01:15

Routh-Hurwitz Criterion I

395
Consider an electrical power grid, where stability is essential to prevent blackouts. The Routh-Hurwitz criterion is a valuable tool for assessing system stability under varying load conditions or faults. By analyzing the closed-loop transfer function, the Routh-Hurwitz criterion helps determine whether the system remains stable.
To apply the Routh-Hurwitz criterion, a Routh table is constructed. The table's rows are labeled with powers of the complex frequency variable s, starting from the...
395
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

889
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
889
Quadratic Models01:23

Quadratic Models

55
Quadratic models are mathematical representations used to describe relationships in which the rate of change changes at a constant rate. These models appear in a wide variety of natural and engineered systems, especially those involving motion, forces, and optimization. One common application is analyzing the vertical motion of objects influenced by gravity, such as a ball thrown into the air.In such scenarios, the object's height changes over time in a curved pattern, rising to a maximum point...
55

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanism of ferroptosis in progressive injury of skeletal muscle caused by high-voltage electrical burns and the intervention effect of uAMC3203.

Burns : journal of the International Society for Burn Injuries·2026
Same author

Spinal cord-like hypertension syndrome with metabolic acidosis and pulmonary edema following lumbar discectomy under general anesthesia: a case report.

BMC anesthesiology·2026
Same author

Machine learning and SHAP interpretation for predicting coronary heart disease-diabetes comorbidity with dietary antioxidants.

Scientific reports·2026
Same author

Association between oxidative balance score and cardiometabolic multimorbidity: differential mortality, mediation mechanisms, and machine learning insights.

Journal of translational medicine·2026
Same author

Non-traditional metabolic indices predict incident circadian syndrome in middle-aged and older Chinese adults: a nationwide prospective cohort study and machine learning analysis.

Lipids in health and disease·2026
Same author

Real-time soybean pest detection system integrating UAV and Jetson based on improved YOLO.

Neural networks : the official journal of the International Neural Network Society·2026
Same journal

An Evolutionary Algorithm Assisted by an Ensemble of Pareto-Optimal Surrogate Models.

IEEE transactions on cybernetics·2026
Same journal

A Quantum Self-Attention Neural Network Model on Quantum Circuits.

IEEE transactions on cybernetics·2026
Same journal

Semi-Explicit Solution of Some Discrete-Time Higher-Order-Cost Mean-Field-Type Control.

IEEE transactions on cybernetics·2026
Same journal

A Novel One-Step Small Object Detector for Autonomous Aerial Vehicles.

IEEE transactions on cybernetics·2026
Same journal

Online Data-Driven-Based Optimal Output Tracking Control Without Initial Stabilizing Policy.

IEEE transactions on cybernetics·2026
Same journal

Digital Redesign-Based Interval State Estimation for Continuous Systems With Aperiodic Discrete Measurements.

IEEE transactions on cybernetics·2026
See all related articles

Related Experiment Video

Updated: Nov 12, 2025

Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
06:00

Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development

Published on: March 17, 2023

647

A Three-Level Radial Basis Function Method for Expensive Optimization.

Genghui Li, Qingfu Zhang, Qiuzhen Lin

    IEEE Transactions on Cybernetics
    |March 22, 2021
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel three-level radial basis function (TLRBF)-assisted algorithm for efficient expensive optimization. The method combines global, subregion, and local searches to enhance performance on complex problems.

    More Related Videos

    Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
    04:35

    Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

    Published on: July 3, 2020

    3.5K
    Topographical Estimation of Visual Population Receptive Fields by fMRI
    06:02

    Topographical Estimation of Visual Population Receptive Fields by fMRI

    Published on: February 3, 2015

    9.5K

    Related Experiment Videos

    Last Updated: Nov 12, 2025

    Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
    06:00

    Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development

    Published on: March 17, 2023

    647
    Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
    04:35

    Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

    Published on: July 3, 2020

    3.5K
    Topographical Estimation of Visual Population Receptive Fields by fMRI
    06:02

    Topographical Estimation of Visual Population Receptive Fields by fMRI

    Published on: February 3, 2015

    9.5K

    Area of Science:

    • Computational intelligence
    • Optimization algorithms
    • Machine learning

    Background:

    • Expensive optimization problems pose significant computational challenges.
    • Existing algorithms may struggle with efficiency and accuracy in high-dimensional or complex search spaces.
    • Radial basis function (RBF) approximations offer a flexible approach for modeling complex functions.

    Purpose of the Study:

    • To develop and evaluate a novel three-level radial basis function (TLRBF)-assisted optimization algorithm.
    • To address the challenges of computationally expensive optimization problems.
    • To improve the efficiency and effectiveness of optimization algorithms in complex scenarios.

    Main Methods:

    • The proposed algorithm integrates three distinct search strategies within each iteration: global exploration, subregion search using fuzzy clustering, and local exploitation.
    • Radial basis function (RBF) approximation models are employed at different levels of the search process.
    • The algorithm optimizes RBF approximations under distance constraints and within localized subregions.

    Main Results:

    • The TLRBF-assisted algorithm demonstrated strong performance on benchmark problems, including scalable problems and CEC2015 computationally expensive problems.
    • The algorithm achieved favorable results on a real-world airfoil design optimization task.
    • Comparative analysis indicated superior performance against other state-of-the-art algorithms for expensive optimization.

    Conclusions:

    • The proposed three-level RBF-assisted optimization algorithm is effective for computationally expensive optimization tasks.
    • The hybrid approach combining global, subregion, and local searches enhances optimization efficiency.
    • The algorithm shows promise for both theoretical benchmark problems and practical engineering design optimization.