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Detection of HIV-1 RNA sequences by in vitro DNA amplification

B C Byrne1, J J Li, J Sninsky

  • 1Department of Medicine, State University of New York Health Science Center, Syracuse 13210.

Nucleic Acids Research
|May 11, 1988
PubMed
Abstract

No abstract available in PubMed .

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In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...