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Updated: Nov 12, 2025

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Introduction of precordial Doppler ultrasound to confirm correct peripheral venous access during general anesthesia
Taiki Kojima1, Kana Kitamura1, Shogo Ichiyanagi1
1Department of Anesthesiology, Aichi Children's Health and Medical Center, Aichi, Japan.
Insights
Precordial Doppler ultrasound accurately confirms peripheral intravenous (PIV) access in children during general anesthesia, aiding in early detection of PIV dysfunction and infiltration.
Area of Science:
- Pediatric Anesthesiology
- Medical Ultrasound
- Vascular Access
Background:
- Delayed identification of peripheral intravenous (PIV) access issues can cause serious complications in pediatric general anesthesia.
- This study addresses the need for accurate PIV assessment in children.
Purpose of the Study:
- To describe the application of precordial Doppler ultrasound for detecting and confirming correct PIV access in children undergoing general anesthesia.
- To evaluate the accuracy of precordial Doppler ultrasound in identifying PIV infiltration and dysfunction.
Main Methods:
- A single-center preliminary study involving children (<18 years) scheduled for elective surgery.
- Anesthesiologists assessed changes in precordial Doppler sound (S test) and blood flow velocity (V test) after saline injection via PIV.
- Sensitivity, specificity, likelihood ratios, and AUC were calculated to determine accuracy.
Main Results:
- The incidence of PIV infiltration/dysfunction was 1.4% (7/512).
- The S test showed 71.4% sensitivity and 97.0% specificity (AUC 0.84).
- The V test (threshold 1.0 m/s) demonstrated 57.1% sensitivity and 96.8% specificity (AUC 0.84).
Conclusions:
- Precordial Doppler ultrasound is a feasible, noninvasive method for confirming PIV access in pediatric anesthesia.
- The technique shows good accuracy in detecting PIV issues.
- Further evaluation is needed to confirm its diagnostic performance.
Background:
Delayed identification of infiltration and dysfunction of peripheral intravenous (PIV) access can lead to serious consequences during general anesthesia in children. This preliminary study aimed to describe the application of precordial Doppler ultrasound during general anesthesia in children to detect and confirm the correct PIV access and to evaluate the accuracy of this method.
Methods:
This was a single-center, preliminary study that was conducted in children (<18 years) who were scheduled for elective surgeries between October 2019 and March 2020. Rater anesthesiologists judged the change in precordial Doppler sound (S test) before and after injection of 0.5 mL/kg of normal saline (NS) via PIV. Blood flow velocity before and after NS injection was recorded, and multiple cutoff points were set to analyze the accuracy of detecting the infiltration and dysfunction of PIV catheter (V test).
Results:
The total incidence of peripheral infiltration and dysfunction of PIV catheter was 7/512 (1.4%). In the S test, the sensitivity, specificity, positive and negative likelihood ratios, and area under the receiver-operating characteristic curves (AUCs) were 5/7 (71.4%; 95% confidence interval [CI], 29.0%-96.3%), 490/505 (97.0%; 95% CI, 95.1%-98.3%), 24.0, 0.29, and 0.84, respectively. The V test showed that the reasonable threshold of blood flow velocity change was 1.0 m/s, with sensitivity, specificity, positive and negative likelihood ratios, and AUC of 4/7 (57.1%; 95% CI, 18.4%-90.1%), 489/505 (96.8%; 95% CI, 94.9%-98.2%), 18.0 and 0.44, and 0.84, respectively.
Conclusions:
This preliminary study demonstrated that precordial Doppler ultrasound is a feasible, easy-to-use, and noninvasive technique with good accuracy to confirm the correct PIV access during general anesthesia in children. However, its accuracy requires further evaluation.
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