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Updated: Nov 11, 2025

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Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
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Spectacle non-tolerance in clinical practice - a systematic review with meta-analysis
Jeewanand Bist1, Dinesh Kaphle2, Sanjay Marasini3
1Tilganga Institute of Ophthalmology, Gausala, Nepal.
Summary
Spectacle non-tolerance affects 2.1% of patients, often due to refraction errors. Understanding these causes is crucial for improving vision care and patient satisfaction.
Area of Science:
- Ophthalmology
- Optometry
- Public Health
Background:
- Spectacle non-tolerance presents significant challenges for patients and eye care practitioners.
- Addressing spectacle non-tolerance is vital to prevent vision impairment and maintain practice reputation.
Purpose of the Study:
- To systematically review the prevalence and identify the primary causes of spectacle non-tolerance in clinical practice.
Main Methods:
- A systematic review of quantitative studies published in English up to July 2020.
- Searches conducted in PubMed, Scopus, and Web of Science databases.
- Quality assessment using a modified Newcastle-Ottawa Scale; pooled prevalence calculated using MetaXL software.
Main Results:
- Five studies involving 205,478 participants were included.
- The pooled prevalence of spectacle non-tolerance was 2.1% (95% CI: 1.6-2.7).
- Refractive errors (47.4%) were the leading cause, followed by communication (16.3%) and dispensing errors (13.5%).
Conclusions:
- Spectacle non-tolerance is influenced by factors in prescription, dispensing, and patient adaptation.
- Vigilance in spectacle prescription and dispensing is necessary to minimize non-tolerance.
- Further research, particularly in under-resourced areas, is needed to enhance refractive error services.
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