Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Estimating a treatment effect under biased sampling.

H Robbins1, C H Zhang

  • 1Institute of Biostatistics, Rutgers University, New Brunswick, NJ 08903.

Proceedings of the National Academy of Sciences of the United States of America
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Research and development progress of pneumococcal conjugate vaccines based on the serotype distribution characteristics of pneumococci in China].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2026
Same author

[Analysis of the immunization status and related factors for children aged 0-7 years old with special health status in Tianhe District, Guangzhou City from 2023 to 2024].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2025
Same author

[Expert recommendations on mass population vaccination].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2025
Same author

[Analysis on personal protection in occupational population at high risk for brucellosis and influencing factor in China].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2024
Same author

[New progress in the first-line treatment of advanced hepatocellular carcinoma].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2024
Same author

[Clinical analysis of 10 cases of multi-center tumor necrosis factor receptor-associated periodic syndrome].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2023
Same journal

In This Issue.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Otsuki et al., Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Hive mind: Microbial communities and the making of memory.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Targets for disease modification in schizophrenia: New findings add to evidence for the involvement of the immune complement system.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Wang et al., The role of reduced aerosol masking from air pollutant emission reductions in recent global warming acceleration (2013-2023).

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Mishra, Ecology is not yet ready for AI-and why that matters.

Proceedings of the National Academy of Sciences of the United States of America·2026
See all related articles

This study introduces a method to estimate treatment effects using pre- and post-treatment data. It focuses on ethically treating only patients with high baseline values, improving intervention efficiency.

Area of Science:

  • Biostatistics
  • Clinical Trial Design
  • Medical Research Methodology

Background:

  • Estimating treatment effects is crucial for clinical decision-making.
  • Ethical considerations often necessitate selective patient treatment.
  • Before-and-after measurements are common in clinical studies.

Purpose of the Study:

  • To develop a statistical method for estimating treatment effects.
  • To account for ethical constraints in patient selection for treatment.
  • To analyze data from studies where only patients exceeding a threshold receive treatment.

Main Methods:

  • The study presents methods for treatment effect estimation.
  • It utilizes before- and after-treatment patient values.
  • A specific threshold for baseline values determines treatment eligibility.

Related Experiment Videos

Main Results:

  • The proposed methods allow for the estimation of treatment effects under selective treatment criteria.
  • The approach is applicable to situations with ethical limitations on patient access to treatment.
  • The methodology provides a framework for analyzing such specific clinical scenarios.

Conclusions:

  • The presented methods offer a robust way to estimate treatment effects in ethically constrained clinical settings.
  • This approach enhances the validity of treatment effect estimation when only a subset of patients is treated.
  • The findings are relevant for designing and analyzing clinical trials with specific inclusion criteria based on baseline measurements.