Comorbidities and functional impairments in children with attention deficit hyperactivity disorder in China: a

Xiaoyan Shi1, Yiting Ji1, Shizhong Cai2

  • 1Department of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China.

BMJ Open
|March 23, 2021
PubMed

Insights

Children with ADHD experience more comorbidities and functional impairments. Comorbidities significantly worsen functional impairment, impacting various life domains more than core ADHD symptoms. Comprehensive clinical management is crucial.

Area of Science:

  • Pediatric Psychology
  • Neurodevelopmental Disorders
  • Child Psychiatry

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children.
  • Understanding comorbidity patterns and their impact on functional impairment is critical for effective management.
  • Previous research highlights the challenges faced by children with ADHD in various life domains.

Purpose of the Study:

  • To assess and compare comorbidity patterns and functional impairment in children with and without ADHD.
  • To investigate the influence of comorbidities on functional impairment in children diagnosed with ADHD.

Main Methods:

  • Retrospective cross-sectional study involving 8256 children and adolescents aged 6-17 years in China.
  • Data collected between 2016-2019 using Vanderbilt ADHD Diagnostic Parent Rating Scale and Weiss Functional Impairment Rating Scale-Parent Form.
  • Participants were divided into ADHD (n=5640) and non-ADHD (N-ADHD, n=2616) groups.

Main Results:

  • The ADHD group exhibited significantly higher rates of comorbidities (47.4%) and functional impairments (84.5%) compared to the N-ADHD group (p≤0.001).
  • Functional impairment scores were significantly higher across all six domains (family, academic, life skills, self-concept, social, risky activities) in the ADHD group (p≤0.001).
  • Comorbidities exacerbated functional impairment in the ADHD group, with their impact exceeding that of core ADHD symptoms on all functional domains.

Conclusions:

  • Comorbidities play a substantial role in adaptive functioning deficits among children with ADHD.
  • Clinical management strategies for suspected ADHD should integrate assessment of core symptoms, comorbidities, and functional impairments.
  • Addressing multiple comorbidities is essential for improving outcomes in children with ADHD.
Abstract

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