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Comorbidities and functional impairments in children with attention deficit hyperactivity disorder in China: a
Xiaoyan Shi1, Yiting Ji1, Shizhong Cai2
1Department of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, China.
Insights
Children with ADHD experience more comorbidities and functional impairments. Comorbidities significantly worsen functional impairment, impacting various life domains more than core ADHD symptoms. Comprehensive clinical management is crucial.
Area of Science:
- Pediatric Psychology
- Neurodevelopmental Disorders
- Child Psychiatry
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children.
- Understanding comorbidity patterns and their impact on functional impairment is critical for effective management.
- Previous research highlights the challenges faced by children with ADHD in various life domains.
Purpose of the Study:
- To assess and compare comorbidity patterns and functional impairment in children with and without ADHD.
- To investigate the influence of comorbidities on functional impairment in children diagnosed with ADHD.
Main Methods:
- Retrospective cross-sectional study involving 8256 children and adolescents aged 6-17 years in China.
- Data collected between 2016-2019 using Vanderbilt ADHD Diagnostic Parent Rating Scale and Weiss Functional Impairment Rating Scale-Parent Form.
- Participants were divided into ADHD (n=5640) and non-ADHD (N-ADHD, n=2616) groups.
Main Results:
- The ADHD group exhibited significantly higher rates of comorbidities (47.4%) and functional impairments (84.5%) compared to the N-ADHD group (p≤0.001).
- Functional impairment scores were significantly higher across all six domains (family, academic, life skills, self-concept, social, risky activities) in the ADHD group (p≤0.001).
- Comorbidities exacerbated functional impairment in the ADHD group, with their impact exceeding that of core ADHD symptoms on all functional domains.
Conclusions:
- Comorbidities play a substantial role in adaptive functioning deficits among children with ADHD.
- Clinical management strategies for suspected ADHD should integrate assessment of core symptoms, comorbidities, and functional impairments.
- Addressing multiple comorbidities is essential for improving outcomes in children with ADHD.
Objectives:
The aim of this study was to assess comorbidity patterns and functional impairment in children with and without attention deficit hyperactivity disorder (ADHD).
Design:
Hospital-based retrospective cross-sectional study; data collection occurred between 2016 and 2019.
Settings And Patients:
A total of 8256 children and adolescents, 6-17 years of age, with suspected ADHD agreed to participate in this hospital-based cross-sectional study over a 4-year period in China. Comorbidities and social functions were assessed according to the scales Vanderbilt ADHD Diagnostic Parent Rating Scale and Weiss Functional Impairment Rating Scale-Parent Form, which were completed by the parents of the study participants.
Results:
Of the 8256 children, 5640 were diagnosed with ADHD. Other 2616 children who did not meet the ADHD diagnostic criteria were classified as the N-ADHD group . The proportion of comorbidities (47.4%) and functional impairments (84.5%) in the ADHD group were higher than the N-ADHD group (p≤0.001). The functional impairment scores in all of the six domains, including family, academic, life skills, self-concept, social activities and risky activities, were significantly higher in the ADHD group than the N-ADHD group (p≤0.001). The functional impairment in ADHD group with comorbidities was more severe than those without comorbidities (p≤0.001). Comorbidities and core symptoms both can affect the functions of children with ADHD. Logistics regression analysis indicated that in all of the six functional domains, the effect of comorbidities on functional impairment exceeded the effects of ADHD core symptoms.
Conclusions:
Comorbidities had the greatest influence on different areas of adaptive functioning in children with ADHD. Clinical management of children suspected to have ADHD should address multiple comorbidities and functional impairments assessment, as well as core symptom analysis.
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