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Rheumatological manifestations in patients hospitalized with COVID-19 in a tertiary care setting
Syed Hassan Mustafa1, Muhammad Umer Farooq1, Farah Iqbal1
1Department of Gynaecology and Obstetrics, Ayub Teaching Hospital, Abbottabad, Pakistan.
Insights
Severe COVID-19 (Coronavirus Disease 2019) patients frequently experienced arthralgia (joint pain) and myalgia (muscle pain). However, arthritis was not observed in any patient requiring oxygen therapy.
Area of Science:
- Rheumatology
- Infectious Diseases
- Internal Medicine
Background:
- Coronavirus Disease 2019 (COVID-19), caused by SARS-nCoV-2, is a global pandemic with diverse organ system involvement.
- The study addresses the need to understand the rheumatological manifestations of severe COVID-19.
Purpose of the Study:
- To investigate the prevalence of rheumatological symptoms in hospitalized COVID-19 patients requiring oxygen therapy.
- To specifically identify arthralgia, myalgia, and arthritis in this patient cohort.
Main Methods:
- A cross-sectional study was conducted at Lady Reading Hospital, Peshawar.
- 141 hospitalized COVID-19 patients needing oxygen and with no prior rheumatological conditions were enrolled.
- Patients were assessed for rheumatological manifestations.
Main Results:
- The study included 141 patients (62.4% male, 37.6% female) aged 27-88 years (mean 58.5).
- Arthralgia (90.8%) and myalgia (84.4%) were highly prevalent among patients.
- No cases of arthritis were reported in any of the participants.
Conclusions:
- Severe COVID-19 cases requiring oxygen therapy commonly present with arthralgia and myalgia.
- Unlike other viral infections, arthritis was notably absent in patients with severe COVID-19 in this study.
Background:
Corona virus disease 2019 (COVID-19) is a pandemic affecting over 150 million people worldwide since its emergence in Wuhan, China in December 2019, and is leading to over 600 thousand deaths. Severe acute respiratory syndrome novel coronavirus 2 (SARS-nCoV-2) causes a wide range of symptoms by affecting different organ systems of the body. This study was designed to specifically look for its rheumatological manifestations.
Methods:
It was a cross-sectional study conducted in the corona complex MTI Lady Reading Hospital Peshawar. A total of 141 COVID-19 positive hospitalized patients requiring oxygen therapy and having no previous rheumatological diseases were enrolled and studied for any rheumatological manifestations.
Results:
There were 88 (62.4%) males and 53 (37.6%) females, with age range from 27-88 years, and mean age of 58.5±11.5 SD. Arthralgia and myalgia were found very common, occurring in 128 (90.8%) and 119 (84.4%) of patients. Arthritis was not found in any patient.
Conclusion:
Arthralgia and myalgia were reported frequently in patients with severe COVID-19 requiring oxygen therapy, while arthritis was not present even in a single patient as is reported in other viral infections.
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