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Updated: Nov 11, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Influence of Positional Isomerism on the Chiroptical Properties of Functional Aromatic Oligoamide Foldamers
Kevin Moreno1, Eric Merlet2, Nathan McClenaghan1
1Institut des Sciences Moléculaires, UMR 5255 CNRS, Université de Bordeaux, 351 Cours de la Libération, 33405, Talence Cedex, France.
Abstract:
A series of functionalized quinoline-based aromatic oligoamide foldamers were prepared in their two enantiomeric forms, comprising an enantiopure terminal camphanyl chiral inducer, which governed the adjacent (P-/M-) helical-handedness. Hierarchical chirality transfer was further investigated in chromophore-appended variants via a range of electronic and vibrational spectroscopic techniques, including circularly polarized luminescence, vibrational circular dichroism and fluorescence. Intense total and polarized photoluminescence (up to Φlum =0.39, glum =1.5×10-3 ) was observed in the visible region from these modular multicomponent architectures and a significant influence of positional isomerism was evidenced. The optimal position of a fluorophore substituent on the quinoline hexamers was determined as being position 2 over position 6, as stronger chiroptical features were systematically observed with the 2-positioned derivatives.
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