Related Experiment Video

Updated: Nov 11, 2025

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
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Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy

Published on: October 16, 2013

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Evolving Surgical Management for Early-Onset Scoliosis in Spinal Muscular Atrophy Type 1 Given Improvements in

Joseph P Drain1, Christopher A Iobst1,2, Reid Chambers2

  • 1Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, Ohio.

JBJS Case Connector
|March 23, 2021
PubMed

Insights

Magnetic growing rods successfully managed scoliosis in an 18-month-old with spinal muscular atrophy (SMA) type 1. This case highlights effective treatment for early-onset scoliosis in young SMA patients.

Area of Science:

  • Pediatric Orthopedics
  • Neuromuscular Disorders
  • Spinal Surgery

Background:

  • Early-onset scoliosis is a significant complication in spinal muscular atrophy (SMA) type 1.
  • Improved medical care has increased life expectancy for SMA type 1 patients, necessitating effective scoliosis management.

Observation:

  • An 18-month-old child diagnosed with SMA type 1 presented with rapidly progressive early-onset scoliosis.
  • This patient represents the youngest known implantation of magnetic growing rods for scoliosis in an SMA patient.

Findings:

  • Magnetic growing rods provided successful management of rapidly progressive scoliosis in this pediatric SMA case.
  • The case details technical challenges, potential complications, and the positive outcome of this early intervention.

Implications:

  • Growing-rod constructs are a viable option for managing scoliosis in SMA type 1 patients with extended lifespans.
  • This case demonstrates the feasibility and success of early magnetic growing rod implantation in very young children with SMA and severe scoliosis.
Abstract

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