Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Image-derived and physiological markers to predict adequate adenosine-induced hyperemic response in Rubidium-82 myocardial perfusion imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2022
Same author

Prospective Phase II Trial of Prognostication by <sup>68</sup>Ga-NOTA-AE105 uPAR PET in Patients with Neuroendocrine Neoplasms: Implications for uPAR-Targeted Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2022
Same author

Randomized Controlled Trial of the Hemodynamic Effects of Empagliflozin in Patients With Type 2 Diabetes at High Cardiovascular Risk: The SIMPLE Trial.

Diabetes·2022
Same author

Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists.

Journal of controlled release : official journal of the Controlled Release Society·2022
Same author

The Association Between Cardiovascular Autonomic Function and Changes in Kidney and Myocardial Function in Type 2 Diabetes and Healthy Controls.

Frontiers in endocrinology·2021
Same author

Effect of 26 Weeks of Liraglutide Treatment on Coronary Artery Inflammation in Type 2 Diabetes Quantified by [<sup>64</sup>Cu]Cu-DOTATATE PET/CT: Results from the LIRAFLAME Trial.

Frontiers in endocrinology·2021
Same journal

[<sup>18</sup>F]MNI-1054, a novel PET ligand for lysine-specific histone demethylase 1 A (LSD1): first-in human validation and enzyme occupancy of the LSD1 inhibitor TAK-418.

EJNMMI research·2026
Same journal

Automatic lesion segmentation in ⁶⁸Ga-PSMA PET/CT and ¹⁷⁷Lu-PSMA SPECT/CT: added value of PET-guided SPECT in a bicentric study.

EJNMMI research·2026
Same journal

The impact of PSMA-PET/CT on clinical decision-making in primary staging of prostate cancer.

EJNMMI research·2026
Same journal

Can chatGPT-4o reliably standardize PSMA PET/CT and PET/MRI reports using PROMISE V2 criteria? - An exploratory study.

EJNMMI research·2026
Same journal

Long-term outcomes in medullary thyroid cancer patients treated with [<sup>177</sup>Lu]Lu-DOTAGA.FAPi dimer therapy.

EJNMMI research·2026
Same journal

Construction and clinical application of a predictive model for the efficacy of ¹³¹I therapy in refractory Graves' disease in children and adolescents.

EJNMMI research·2026
See all related articles

Related Experiment Video

Updated: Nov 11, 2025

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.5K

Carotid plaque inflammatory activity assessed by 2-[18F]FDG-PET imaging decrease after a neurological thromboembolic

Laerke Urbak1, Rasmus S Ripa2, Benjamin V Sandholt3

  • 1Department of Vascular Surgery, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark. laerke.urbak.01@regionh.dk.

EJNMMI Research
|March 23, 2021
PubMed
Summary
This summary is machine-generated.

Carotid plaque inflammation decreased three months after a thromboembolic event, indicating stabilization. However, 3D ultrasound did not detect significant changes in plaque morphology using grayscale median (GSM).

Keywords:
3D ultrasoundCarotid artery plaqueFDG PETInflammationVulnerable plaque

More Related Videos

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke
12:01

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

Published on: June 14, 2018

13.0K
Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
10:31

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

14.2K

Related Experiment Videos

Last Updated: Nov 11, 2025

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.5K
PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke
12:01

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

Published on: June 14, 2018

13.0K
Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
10:31

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

14.2K

Area of Science:

  • Cardiovascular Imaging
  • Nuclear Medicine
  • Vascular Ultrasound

Background:

  • Atherosclerotic plaque vulnerability is influenced by inflammatory activity.
  • 3D ultrasound and 2-[18F]FDG-PET can depict plaque composition and inflammation.
  • Timely changes in carotid artery plaque inflammation and morphology post-event were investigated.

Purpose of the Study:

  • To assess changes in carotid artery plaque inflammation and morphology after a thromboembolic event.
  • To evaluate the utility of 2-[18F]FDG-PET/CT and 3D ultrasound in depicting these changes.
  • To determine if plaque inflammation and morphology stabilize over three months.

Main Methods:

  • Prospective inclusion of patients with neurological symptoms and ipsilateral carotid plaque.
  • Sequential 2-[18F]FDG PET/CT and 3D ultrasound scans of the plaque.
  • Measurement of maximum standardized uptake value (SUVmax) on PET/CT and volumetric grayscale median (GSM) on ultrasound.

Main Results:

  • A statistically significant decrease in average SUVmax (plaque inflammation) from baseline to 3-month follow-up (P=0.034).
  • No significant increase in grayscale median (GSM) values over the 3-month period (P=0.808).
  • Mean time to baseline scan was 7 days, and follow-up was 98 days.

Conclusions:

  • Decreased 2-[18F]FDG uptake indicates reduced inflammatory activity, suggesting carotid plaque stabilization post-event.
  • 3D ultrasound quantitative morphological differences (GSM) were not detectable at 3 months.
  • PET/CT is a valuable tool for assessing plaque inflammation changes over time.