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Serotoninergic system targeting in multiple sclerosis: the prospective for pathogenetic therapy.

Mikhail Melnikov1, Anastasiya Sviridova2, Vladimir Rogovskii2

  • 1Department of Neuroimmunology, Federal Center of Brain research and Neurotechnology of the Federal Medical-Biological Agency of Russia; Department of Neurology, Neurosurgery and Medical Genetics and Department of Molecular Pharmacology and Radiobiology, Pirogov Russian National Research Medical University, Moscow, Russia; Laboratory of Clinical Immunology, National Research Center Institute of Immunology of the Federal Medical-Biological Agency of Russia, Moscow, Russia.

Multiple Sclerosis and Related Disorders
|March 23, 2021
PubMed
Summary

Serotonin (5-hydroxytryptamine) influences central nervous system inflammation, particularly in multiple sclerosis (MS). This review explores serotonin

Keywords:
5-HTSSRIsTh17-cells, multiple sclerosisgut-brain axisneuroimmune interaction

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