Assessment of retinal microvascular health by optical coherence tomography angiography among persons with HIV
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Updated: Nov 11, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Lauren F Collins1,2, Jessica G Shantha3, Peter L Nesper4
1Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine.
Abstract:
Microvasculopathy may link HIV-related chronic inflammation and premature multimorbidity. In this proof-of-concept study, we used optical coherence tomography angiography (OCTA) to evaluate the retina as a convenient assessment of microvascular health among persons with HIV (PWH) undergoing surveillance ophthalmic care at Emory from 2018 to 2021. Among patients with longstanding HIV, OCTA identified microvascular abnormalities even among eyes without clinical retinal disease. Retinovascular evaluation by OCTA is a feasible, noninvasive technique for assessing microvasculopathy among PWH.

