Related Experiment Video

Updated: Nov 11, 2025

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
05:57

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection

Published on: February 10, 2017

8.7K

Oral submucous fibrosis in children: an alarming condition and challenges in management

Anshul Rai1, Anuj Jain2, Aakash Arora3

  • 1Dentistry, All India Institute of Medical Science - Bhopal, Bhopal, Madhya Pradesh, India anshulrai007@yahoo.co.in.

BMJ Case Reports
|March 24, 2021
PubMed

Insights

Oral submucous fibrosis (OSF), a potentially malignant condition, is increasingly seen in children due to tobacco use. Early diagnosis and conservative management, including physiotherapy and counseling, improve outcomes in pediatric OSF cases.

Area of Science:

  • Oral Medicine
  • Oncology
  • Pediatric Dentistry

Background:

  • Oral submucous fibrosis (OSF) is a recognized potentially malignant disorder, predominantly affecting adults in the Indian subcontinent.
  • Pediatric cases of OSF are rare, with limited literature available on their specific characteristics and management.
  • This study addresses the underrepresentation of pediatric OSF in research by presenting case studies and a comprehensive review.

Purpose of the Study:

  • To present three cases of oral submucous fibrosis in children under 12 years of age.
  • To review the etiology, clinical presentation, and treatment strategies for pediatric OSF.
  • To highlight the importance of early diagnosis and management in improving patient outcomes.

Main Methods:

  • Case report analysis of three pediatric patients diagnosed with OSF.
  • Literature review focusing on the etiology, clinical manifestations, and treatment of OSF in children.
  • Evaluation of treatment outcomes, including mouth opening and patient follow-up.

Main Results:

  • Clinical features such as restricted mouth opening, burning sensation, and betel nut chewing history were key diagnostic indicators.
  • Histopathological examination confirmed the diagnosis in all reported cases.
  • Conservative management combined with oral physiotherapy led to improved mouth opening and functional recovery.

Conclusions:

  • Children are increasingly exposed to and using tobacco products, contributing to the rise in pediatric OSF.
  • Early detection and intervention, including conservative management and counseling, are crucial for managing pediatric OSF.
  • Further research with larger sample sizes is necessary to fully understand and address the prevalence and impact of pediatric OSF.

Keywords:
dentistry and oral medicinesmoking and tobacco

More Related Videos

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies05:42

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

1.4K
Tissue Engineering of the Intestine in a Murine Model08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

15.2K

Related Concept Videos

Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
305
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
230
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
294
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
430
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
583
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
168