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Surgical Outcomes of Primary Congenital Glaucoma in Children Under One Year from the Nile Delta

Mohamed F Farid1, Mohamed Anany1, Mohamed A Awwad1

  • 1Ophthalmology Department, Benha University, Benha, Egypt.

Clinical Ophthalmology (Auckland, N.Z.)
|March 24, 2021
PubMed

Insights

Surgical management of primary congenital glaucoma (PCG) in infants under one year old in the Nile Delta showed a 72.7% success rate. This treatment had a low incidence of sight-threatening complications, indicating good outcomes for PCG patients.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Glaucoma Research

Background:

  • Primary congenital glaucoma (PCG) is a rare, severe form of glaucoma presenting in infancy.
  • Early surgical intervention is crucial for preserving vision in PCG patients.
  • Understanding regional outcomes is vital for tailoring treatment strategies.

Purpose of the Study:

  • To evaluate the surgical outcomes of primary congenital glaucoma (PCG) in infants under one year of age.
  • To assess the efficacy and safety of surgical interventions for PCG in the Nile Delta population.
  • To determine the success rate and complication profile of PCG surgery in this specific demographic.

Main Methods:

  • Retrospective review of medical records for PCG patients under one year old.
  • Surgical intervention data collection from a tertiary care facility in the Nile Delta.
  • Measurement of intraocular pressure (IOP), corneal diameter, and cup-to-disc ratio pre- and post-surgery.
  • Minimum six-month follow-up period to assess disease progression and surgical success.

Main Results:

  • 44 eyes of 26 infants underwent surgical treatment for PCG, with a mean follow-up of 18.5 months.
  • Postoperative IOP significantly decreased (13.3±4.8 mmHg) compared to preoperative levels (28.5±4 mmHg).
  • Surgical success, defined as IOP < 22mmHg without medication, was achieved in 72.7% (32 eyes); sight-threatening complications occurred in 3 eyes.

Conclusions:

  • Surgical management of PCG in infants (<1 year) in the Nile Delta region demonstrates a good success rate.
  • Visually significant postoperative complications were infrequent, suggesting a favorable safety profile.
  • Further extensive studies with longer follow-up are recommended to fully characterize PCG in this region.
Abstract

Keywords:
Ahmed glaucoma valveintraocular pressureprimary congenital glaucomathe Nile Deltatrabeculectomytrabeculotomy

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