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Published on: July 21, 2011
Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
Eleonora Nucera1, Sara Urbani1, Alessandro Buonomo1
1Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Abstract:
Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
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