Related Experiment Video
Updated: Nov 11, 2025

Swabbing the Urban Environment - A Pipeline for Sampling and Detection of SARS-CoV-2 From Environmental Reservoirs
Published on: April 9, 2021
Ethnicity, household composition and COVID-19 mortality: a national linked data study
Vahé Nafilyan1,2, Nazrul Islam3, Daniel Ayoubkhani1
1Office for National Statistics, Newport, UK.
Objective:
To estimate the proportion of ethnic inequalities explained by living in a multi-generational household.
Design:
Causal mediation analysis.
Setting:
Retrospective data from the 2011 Census linked to Hospital Episode Statistics (2017-2019) and death registration data (up to 30 November 2020).
Participants:
Adults aged 65 years or over living in private households in England from 2 March 2020 until 30 November 2020 (n=10,078,568).
Main Outcome Measures:
Hazard ratios were estimated for COVID-19 death for people living in a multi-generational household compared with people living with another older adult, adjusting for geographic factors, socioeconomic characteristics and pre-pandemic health.
Results:
Living in a multi-generational household was associated with an increased risk of COVID-19 death. After adjusting for confounding factors, the hazard ratios for living in a multi-generational household with dependent children were 1.17 (95% confidence interval [CI] 1.06-1.30) and 1.21 (95% CI 1.06-1.38) for elderly men and women. The hazard ratios for living in a multi-generational household without dependent children were 1.07 (95% CI 1.01-1.13) for elderly men and 1.17 (95% CI 1.07-1.25) for elderly women. Living in a multi-generational household explained about 11% of the elevated risk of COVID-19 death among elderly women from South Asian background, but very little for South Asian men or people in other ethnic minority groups.
Conclusion:
Elderly adults living with younger people are at increased risk of COVID-19 mortality, and this is a contributing factor to the excess risk experienced by older South Asian women compared to White women. Relevant public health interventions should be directed at communities where such multi-generational households are highly prevalent.
Related Concept Videos
Bias in Epidemiological Studies
Statistical Methods for Analyzing Epidemiological Data
Causality in Epidemiology
Longitudinal Studies
Confounding in Epidemiological Studies
Longitudinal Research

