Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A DIA-MS-based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients.

Molecular oncology·2025
Same author

Proteomics of tumor and serum samples from isocitrate dehydrogenase-wildtype glioblastoma patients: is the detoxification of reactive oxygen species associated with shorter survival?

Molecular oncology·2024
Same author

Virtual Reality-Assisted Awake Craniotomy: A Retrospective Study.

Cancers·2023
Same author

Management of Recurrent Glioblastomas: What Can We Learn from the French Glioblastoma Biobank?

Cancers·2022
Same author

A Simple Preoperative Blood Count to Stratify Prognosis in Isocitrate Dehydrogenase-Wildtype Glioblastoma Patients Treated with Radiotherapy plus Concomitant and Adjuvant Temozolomide.

Cancers·2021
Same author

What effects does awake craniotomy have on functional and survival outcomes for glioblastoma patients?

Journal of neuro-oncology·2021

Related Experiment Video

Updated: Nov 11, 2025

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
10:25

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

Published on: September 2, 2025

256

Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study.

Morgane Casanova1, Anne Clavreul2,3, Gwénaëlle Soulard2,3

  • 1Équipe Facial Analysis Synthesis & Tracking Institue of Electronics and Digital Technologies, CentraleSupélec, Rennes, France.

Journal of Medical Internet Research
|March 24, 2021
PubMed
Summary

This study shows that using virtual reality (VR) headsets with eye-tracking during awake brain surgery is safe and feasible. This innovation allows for new VR-based brain mapping of cognitive functions beyond language.

Keywords:
awake surgerybrain mappingeye trackingmobile phonenonverbal languagevirtual realityvisuospatial cognition

More Related Videos

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.0K
Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions
06:18

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions

Published on: April 5, 2024

1.3K

Related Experiment Videos

Last Updated: Nov 11, 2025

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
10:25

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

Published on: September 2, 2025

256
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.0K
Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions
06:18

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions

Published on: April 5, 2024

1.3K

Area of Science:

  • Neurosurgery
  • Cognitive Neuroscience
  • Virtual Reality Technology

Background:

  • Awake brain surgery typically maps language but neglects other social cognition functions like visuospatial skills and nonverbal communication.
  • Existing mapping tasks are often incompatible with the constraints of awake surgery environments.
  • There's a need for novel methods to assess these crucial cognitive functions during surgery.

Purpose of the Study:

  • To assess the safety and feasibility of using a virtual reality headset with eye-tracking for patients undergoing awake craniotomy.
  • To provide an immersive visuospatial and social virtual reality (VR) experience during surgery.
  • To explore VR as a tool for mapping cognitive functions beyond language.

Main Methods:

  • Recruited 15 patients with brain tumors near critical language/motor areas.
  • Performed language mapping using a naming task (DO 80) on a tablet and within VR (2D/3D).
  • Immersed patients in a visuospatial and social VR experience, with eye-tracking data collected.

Main Results:

  • No patients reported VR sickness; two experienced seizures unrelated to VR.
  • Patients successfully completed VR tasks, demonstrating feasibility.
  • Eye-tracking data provided insights into patient attention and visual exploration within the VR environment.

Conclusions:

  • Immersive VR environments can be safely utilized during awake brain surgery.
  • This approach enables new VR-based brain mapping for cognitive functions.
  • The technology facilitates the assessment of visuospatial and social cognition in surgical patients.