Related Experiment Video

Updated: Nov 11, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.7K

Multisystem Inflammatory Syndrome in Children, Chile, May-August 2020

Carmen Niño-Taravilla, Hugo Otaola-Arca, Natalie Lara-Aguilera

    Emerging Infectious Diseases
    |March 24, 2021
    PubMed

    Insights

    Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 impacted pediatric intensive care patients. Most children required significant medical support, but all survived.

    Area of Science:

    • Pediatric critical care medicine
    • Infectious diseases
    • Cardiology

    Background:

    • Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition.
    • COVID-19 has been linked to MIS-C, requiring intensive care evaluation.
    • Understanding MIS-C's impact on pediatric intensive care units (PICUs) is crucial.

    Purpose of the Study:

    • To describe the clinical characteristics and outcomes of children with MIS-C admitted to a PICU.
    • To identify common complications and treatments required for MIS-C patients.

    Main Methods:

    • Retrospective case series.
    • Analysis of 26 children diagnosed with MIS-C.
    • Review of medical records, including ventilation, inotropic support, and echocardiographic findings.

    Main Results:

    • 26 children with MIS-C were admitted to the PICU.
    • 10 (38.5%) required mechanical ventilation.
    • 13 (50.0%) required inotropic support.
    • 18 (69.2%) had echocardiographic abnormalities.
    • No deaths were reported.

    Conclusions:

    • MIS-C in the PICU setting often necessitates intensive respiratory and cardiovascular support.
    • Echocardiographic abnormalities are common in pediatric MIS-C patients.
    • Despite severe illness, favorable outcomes were observed in this cohort, with no mortality.

    Keywords:
    COVID-19ChileKawasaki diseaseMIS-CSARS-CoV-2childrencoronary dilatationscoronavirus diseasecoronavirus disease 2019coronavirusesmultisystem inflammatory syndrome in childrenpediatric intensive care unitsrespiratory infectionssevere acute respiratory syndrome coronavirus 2shockviruseszoonoses

    More Related Videos

    A Standardized Procedure for Monitoring Harmful Algal Blooms in Chile by Metabarcoding Analysis09:47

    A Standardized Procedure for Monitoring Harmful Algal Blooms in Chile by Metabarcoding Analysis

    Published on: August 26, 2021

    5.6K
    Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses09:43

    Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses

    Published on: March 8, 2024

    2.1K

    Related Concept Videos

    Myocarditis II: Clinical Features and Diagnostic Tests01:27

    Myocarditis II: Clinical Features and Diagnostic Tests

    Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
    92
    Immunodeficiency Diseases01:25

    Immunodeficiency Diseases

    Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
    There are three main causes of immunodeficiency...
    1.4K
    Myocarditis III: Medical Management01:14

    Myocarditis III: Medical Management

    Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
    59
    Asthma-III: Symptoms and Complications01:24

    Asthma-III: Symptoms and Complications

    Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
    Classification of Asthma
    2.8K
    Tonsillitis I: Introduction01:30

    Tonsillitis I: Introduction

    Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
    Etiology
    Three primary contributing factors have been identified.
    920