Experimental exposure to alcohol as a model for the evaluation of neurobehavioural tests
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J Hooisma1, D A Twisk, S Platälla
1Medical Biological Laboratory TNO, Rijswijk, The Netherlands.
Toxicology
|May 1, 1988
Abstract:
The performance characteristics of 4 computerized psychological tests were studied using alcohol as a model compound. Subjects received alcohol (0.5 ml/kg) or placebo in a cross-over design and performance was assessed using the Simple Reaction Time test, the Switching Attention test, the Hand/Eye Coordination test and the Color-Word Vigilance test. Analyses indicated an overall significant effect of alcohol at blood-alcohol levels of 0.03% with response speed on the Color-Word Vigilance test being the most sensitive parameter.