Is there evidence for the use of FLT3 inhibitors as maintenance therapy in AML?

Mark Levis1

  • 1Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Department of Oncology, Division of Hematologic Malignancies, United States.

It is often assumed that all patients with FLT3 (FMS-Like Tyrosine kinase-3)-mutated AML who undergo an allogeneic transplant should receive maintenance therapy with a FLT3 inhibitor. The validity of this assumption is controversial.