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Risk compensation after HIV-1 vaccination may accelerate viral adaptation and reduce cost-effectiveness: a modeling

Kathryn Peebles1, John E Mittler2, Steven M Goodreau3,4

  • 1Department of Epidemiology, University of Washington, Seattle, WA, USA.

Scientific Reports
|March 25, 2021
PubMed
Summary

Behavioral risk compensation after HIV vaccination may accelerate viral adaptation, potentially reducing vaccine effectiveness and increasing HIV prevalence over time. This highlights the complex interplay between vaccines, behavior, and pathogen evolution.

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