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Perspectives on Neuroscience
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Letter to the Editor.

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  • 1Department of Population Health, New York University.

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Summary
This summary is machine-generated.

This study illustrates aliasing in statistical modeling using beta and normal distributions. An infinite mixture model, inspired by placebo response, provides a new example of this phenomenon.

Keywords:
aliasingconvolutionmixturesplacebo effect

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Area of Science:

  • Statistics
  • Probability Theory
  • Statistical Modeling

Background:

  • Aliasing is a phenomenon where different models can produce similar results.
  • Previous work by Hutson and Vexler (2018) demonstrated aliasing with beta and normal distributions.
  • Modeling placebo response presents challenges in distinguishing true treatment effects from other factors.

Purpose of the Study:

  • To present a novel illustration of aliasing.
  • To utilize beta and normal distributions in demonstrating aliasing.
  • To explore the application of an infinite mixture model inspired by placebo response data.

Main Methods:

  • The study employs an infinite mixture model.
  • The model incorporates both beta and normal distributions.
  • The methodology is inspired by the complexities of placebo response modeling.

Main Results:

  • A new example of aliasing involving beta and normal distributions is presented.
  • The infinite mixture model successfully illustrates the aliasing phenomenon.
  • The findings highlight potential pitfalls in statistical inference when distributions overlap.

Conclusions:

  • Aliasing can occur with beta and normal distributions, even within complex models.
  • Infinite mixture models offer a framework for understanding aliasing in practical scenarios.
  • Careful model specification is crucial when analyzing data with potential for aliasing, such as placebo response.