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Cerebral Sinus Thrombosis Secondary to SARS-CoV-2 Infection

Mojtaba Khazaei1, Kiana Karimi2,3, Parinaz Sedighi2,3

  • 1Department of Neurology, Hamadan University of Medical Sciences, Hamadan, Iran.

Case Reports in Neurological Medicine
|March 25, 2021
PubMed

Insights

This case report details a COVID-19 patient who developed severe neurological complications, including cerebral venous thrombosis and subarachnoid hemorrhage. Prompt anticoagulant therapy led to a successful recovery, highlighting the importance of recognizing these neurological manifestations.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with a spectrum of neurological complications.
  • Cerebral venous thrombosis is a recognized, albeit rare, neurological manifestation of COVID-19.

Observation:

  • A 57-year-old male presented with headache, seizure, and decreased consciousness three weeks post-COVID-19 diagnosis.
  • Initial management included mechanical ventilation and phenytoin for seizures.
  • Brain imaging revealed right transverse sinus and cortical vein thrombosis with subarachnoid hemorrhage.

Findings:

  • The patient's neurological status and respiratory function improved with anticoagulant therapy.
  • Successful treatment of cerebral venous thrombosis and associated hemorrhage was achieved.

Implications:

  • This case underscores the critical need for heightened awareness of neurological complications in COVID-19 patients.
  • Timely diagnosis and appropriate management, including anticoagulation, are crucial for favorable outcomes.
  • Further research into the mechanisms and optimal treatment strategies for COVID-19-associated neurological events is warranted.

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